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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f4623eacfbb05e4c9144308f2eac91c676bdf1bd687d4d6004437c27222e362' 
  AND token = 'ddhXkJtAnG71DCR0LAcr+3UWNFvREAMNUPnUwXt9BlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}