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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42bfa66a30752d4da0f4898a39b43763265df8d921c8335dec2aa3829657816c' 
  AND token = 'eYFCWQO+OZvi7Gx7RDXfCq0fDinl/+aim3WlTnQaZMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}