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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1db27d26a590d36e2496ea118e607854b1581ca95a1127770d5771f150f52258' 
  AND token = 'kkt6GG1+HmDWsI8MBWKFWeWI+aoMSWq1Nx+4ePZj9v0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}