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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fed0f865bb00c8292cce0a13d8ca38e05efd3ab38b4c1376ce4b36f1ce547de' 
  AND token = 'cIxaJnOItPk8I8Xm9ayxdS5uO2vfldWwr8tYm0+SZmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}