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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b0da5ff4a78d53b8ac51a818ec6d59715d554c1b5edb6ce23a3458e40856c7e' 
  AND token = 'JSxfch2AqgTjVmiqTTSEjSrSUmREvC4mREuXfNq93bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}