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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7e3ea4a3b3cee0d38b2b7d94cd04ccbdacf70ffb49f7188e0b65421bb393b8b' 
  AND token = 'b1Zo9hyJEsGugUj4RNqy5U5DUVsgdOFX9o/flHCmmNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}