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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ae640a02c740bf33d15dbcf03a5ab6d865019ce2aab768a466958328f262684' 
  AND token = 'pfCDh9hs8OteGd1Wb6oiFiEZSIppLoHTzwZEr9jRJI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}