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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af1b536dd402e245ddb3ed84fd7194aec53f4b43e7d256de4c84853f61f7884a' 
  AND token = 'JoJ0Fml3MB5YYyyU1dq36FqFeWjk02b87XjDH6QNwaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}