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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90440b7878f8aed43c1cfb59d8fbfa79c0a23665a54f4e6eb3edb85f2e1bd0a9' 
  AND token = '4Qb5xjjpFs0pOTCKxosc25XAg/GyQl01FlNSlUvAO5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}