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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '244d74b5471d2214bd13fd8f996fa752d5574d8257839186bc8d42179c27867a' 
  AND token = 'kdXBulD9PtOJC5JgAjAiobBy/8EmXxEtOk+6U60Civ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}