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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d217449889c2738d05d299404341e8f2f8031ac44a01fce2d727d0d375ec063' 
  AND token = 'DVmHnejz4JTT3fwIx7IvfboOk8GTlKdNe1Dy6Rmji6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}