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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c41d21d1bc90794fa848efd50de24d7e9f05c106161470e069683ca7b44f8822' 
  AND token = 'Md8TQrtDIcku2FKMLUwzSNGQmWSQIVC6dKGo+texlyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}