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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72d04738d8fe839d5ee6af5f7247c54e978dda7f30f91449095b0e223d1a39f' 
  AND token = '0X8PZ1yfFFLBoR+wA7MhFu2rKFcfVyMcv23ENCCSWvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}