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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27ac46770291708c8b8ec5c15b353f6072a80e5f703da5c93d35ac4fc25aaa33' 
  AND token = '/MloK2fZZ9+Nmqb/Ri/Zf1HBoM73y/Hqp0JKssG1Ry0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}