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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef11ed66736cfedb5cdb7856a5e045cf1a53b7cd5ced955cc457ab573bcb0715' 
  AND token = 'GLoMOUXqV/unmT3arNcFmJ06FVpd6MHhkB2b8KafOjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}