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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '730ae20a2372a390dca0a3e11f6eb8504d0730c20021cbb14fd867fea20cb177' 
  AND token = 'cy4Fe7xlP+8F1G6XDrCewc7YmYAMZ9i2JF+D609FVSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}