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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c224d59aa627170cef2ab9c68a052ac7f075c6654886aff873bde851536eb400' 
  AND token = '9UZflFmVKrfoV+8rViayeJDdWp9uUkLvfurMe3Yr69g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}