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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f486a9c9b495af979f745afd3e4af63c1cb8f7566cca461c378260ed4db87d9f' 
  AND token = 'uliZ69SxYIyfAHvMMbBuMe1sc/LB21jJ3mZce85a4lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}