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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef18e8b3b6245e534cf5dc3010b89d57119d9e7674b0153606af454cc2075f4e' 
  AND token = 'R2HD+wg0WvFkog7l6Jzns5DwvgcqGdaJpealO9HtbNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}