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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f77fd71e235128397a9344100aeaa1e3c9d8749d97e019e1ab34187076f15a0b' 
  AND token = 'h3dIWIpQNstyJx/KHhO9jzd16ltnaJWWdG+cPLi7aOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}