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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a8502a23b0dc70cc5b11e9ae479f35e5624a1c0cc5a689072d387b550ec680e' 
  AND token = '7UKx3AF40JJqiUDToham11VEaXpMQZiFzh4oqFFqTSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}