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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '594e5600a9d0cd5e49623779283df7b36076456029b4c5b95fe392c7902bfa52' 
  AND token = 'TYtw28ooMbdYq38V2Fu4CAXh4lRnB8CyW1c7yTfbHcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}