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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f46c379d669f3c050625310fa86d8ebedd7a027367d6f61d3c0357d9377b37' 
  AND token = 'CHc1tXMRyDqvxq/f3bwLc9Yr/yGd7bUkjNVb9len+oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}