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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40c0bd4ad99eb6d879345af3854e4a2d11dec1433b9c9db1e7a7943be80cb9a2' 
  AND token = 'kvfeDVvgQBFeTZnx2hQCwekGo/dmH23646KsGdxhxvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}