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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c37dac15a97acc23a63e488e129563a53b1a38ac2c3e2eabcecf45ff39ff193' 
  AND token = 'vTkaoVhzSSfV3rgdvDNlXh6RuQ8sehfWdwG2+IyFMq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}