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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c6db1e49fe72a3253bc58fddcd554519b054791a5f6d666af3cc3088276bcb0' 
  AND token = 'x2KJ00ar5TQdUG8BfE85T4HIMaKl7coNLWJ92OqSAmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}