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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457da39805e10614446d684288c0d8e6a04adb388e8c1c3d372f4ad18aa09e72' 
  AND token = 'JtcF9hGEwymE83/DQx5CdjWW1fNZ6qNdLx7ONY++kTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}