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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6454c6296daae91705210ce2654629b7b2e6ee594553e552e9a0d4ee4b4e2fe0' 
  AND token = 'WUJLr47x6SiizNfgpM1eYvmZ9eZTpPevtuPz2UdhC70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}