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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05531e8343434d6e3ea7139865ca6932c66b9864781c5a5547d99c8700ff4f65' 
  AND token = 'zWoBQcKRERiDFe65k0sOTVZrRLeNJGESPNi376d6PNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}