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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44b1b3007f97e535f353cead2fa03551d7ceae3494a49bc6ada8a3fbc7e28adb' 
  AND token = '4OU48pmTDyQ95OTIU0o3vv2gXknQ375jwV97jJiY8cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}