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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '128a155bbe2e3a7b68e7d3efe4bda66a1e103e70ec631598c239f5e9bbdce0f3' 
  AND token = 'ZDZ4VE6idSVp7y2uqZ3Cq45+N9nB36JecLiv9pYQWSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}