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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44574e461cfa2e8006ddd70761e2d0846f37ae659234a1abfff3cb264a6fe2cc' 
  AND token = '2qrZW38hhz5deAwPaI3h3z4Fcf4T3Y1KJRFjZLd++pI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}