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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c08a64a0bf60d8d8b94f7d57ad7e2a97f5764248f70cd3794791295ced6c721' 
  AND token = '/Yeau380/X6MgLR0kFJEaEHBGc4HjSkrEQv0XnnTYkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}