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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de504c51f3218bc2e883dac793700a6e668b482295d0dfc2ad7893742a60dffe' 
  AND token = 'jQvYlTd6ROqeeDS/XzHxV7Uxalghe2dv5zQDpQzIFOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}