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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b74b1fef49dc2d8b1314c34748c6ef525c9d7d2cee5e453a00f01835420da200' 
  AND token = 'rif09TVcipoTPa4K+gxGDd2Vi/aEuqJ0KKqERFx/auY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}