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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64dfcacc782ec4156643212fbbcd2153210cee37d67668aa965584f05d96ce02' 
  AND token = 'bY+fMOvH1gn625PQaTh7solC/HxkAkLRGbVpdKbAsfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}