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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd62e0c3503084adc4ae292eff3c3c8d3380cc230d56081dd9d247991a354fb48' 
  AND token = 'r403zQEoglJgkY/Pt/EeiQ1PEtQHmNMxNUulAVkL3Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}