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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '279d4c7321bf52b06a71b29f1514eaad3187403ff497e926c948bfe74262571b' 
  AND token = 'emD+YExDJ8hMz3d8Rb0Xy881+dO6Tbwe3VH3kzJAXQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}