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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a3bd99c6898a7f21d1610a209649d5d1b6b1699db67ad3397431251cb51da6' 
  AND token = '/+d0cO8lsboy2CVm3sCY2dufpzDam9kvXDgrgf6Vdd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}