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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fe8819596a7b177b4b8199f1209b39feec9fd74f63e64e854aa35399092d074' 
  AND token = 'FCgxF+Tiu7axqCSTsJoXn+xzFzoBMWa9h6NfTqC4gOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}