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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfd497df93497e0bea4f6e936288ca8dd06627fc693aff024bf5b589dd8b0540' 
  AND token = 'p1x+8RiqF+glkVP05dutfwlN5wLfzkZuA9xXAITkdXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}