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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '546b6a2a0bbd2cb421433c2d7137578008a5bd85a5345276e2a6423a16dd91b2' 
  AND token = 'iDITHMjx0Jd7LEwKRrKt0uA1Ln83dtHB+oPlgKb3K8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}