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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5525f1d06d9295a5de59e815014031a0cd2b9e68aaa4d5cddf92e97809d69193' 
  AND token = 'IhRmRfhP96ULQLh8qYbuvR6JSxCWNw+4V/c6LIAgMT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}