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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1fcbc53d145d233c36ab10c4d0815ecb32a9a4cef0894ccb42b3f2e67a75a19' 
  AND token = 'FCqnQK8eaqo3XIfmwlyf96P0QbOPcjbyMfve4xTHUgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}