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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4578e8793f88dea3e40fb10e3e36ed589ce9ff0fd94be8d99eb402c81ff9fde' 
  AND token = 'aE79ZLiS4cFRJekkdYf/uf1DxKpNPSclhhN6ZdCVh5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}