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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b06d0f46b3a95f2742a8d3e7e1fb44f2a5aabfcb75eb68cf488f3b30ff17183' 
  AND token = '+RgN+UU/ucEfyy7Da8pj95SXhE1tQhIvvv+rqWf2ou0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}