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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c00a8e32d0c9758844ce0e216b5170b726481fff0767c7313230ed4a5b2296a' 
  AND token = 'cjDkQ+VIRQ7PevXrO5g29dVte+gUeb+4ALOqVf4tgNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}