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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c5d2f5d11c6c61c65100352fd804a3ba014d859351c3cec71c0b00471c3a5bd' 
  AND token = 'VEKWt5ShC4w3OTgXlG1Wg4eTBXiYxSJMasfnnSCMzSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}