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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a8c7fd5777bf03155f4f47bbf84268fd6bf1599682c269109634a706551459d' 
  AND token = '/Of+cDDVDUbW8R2M2W4+Cf/tsYh+QNhjo59fJSYWnkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}