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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc3de519e71c60825e1861658103a8fd74f24d29a6a693f3bbe221076333578d' 
  AND token = 'jXvGQNaqwsiAi2pPXD241Rrb6qN8G13RKpqhD1VYCgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}